What Is NAD (Nicotinamide Adenine Dinucleotide)?

Nicotinamide Adenine Dinucleotide (NAD+) is a coenzyme that also acts as a neurotransmitter at times. It is in charge of fueling the oxidation of cells in our bodies and is an essential process for every person, especially after the age of 40. After 40, cell oxidation begins to deplete. It is also deficit in persons with addiction and mental health diseases. There are many amazing positive factors that NAD+ brings to the body. It heals the organs and is the most natural way to invigorate, revitalize and restore the brain’s faculties.

The NAD+ coenzyme was first discovered in 1906 by British biochemists Arthur Harden and William John Young. They noticed that adding boiled and filtered yeast extract accelerated alcohol fermentation in unboiled yeast extracts. They called the unidentified factor responsible for this effect a conferment. Then, in 1938, the vitamin precursors of NAD+ were identified when Conrad Elvehjem showed that liver has an “anti-black tongue” activity in the form of nicotinamide. In 1939, the first strong evidence was found that niacin is used to synthesize NAD+. Later, in the 1940’s Arthur Kornberg made another important contribution towards understanding NAD+ metabolism by being the first to detect an enzyme in the biosynthetic pathway.

The metabolism of NAD+ has remained an area of intense research well into the 21st century. In 2000, the discovery of the NAD+ dependent protein deacetylases called sirtuins by Shin-ichiro Imai and coworkers at the Massachusetts Institute of Technology brought heightened interest. David Sinclair from Harvard sensationalized the findings, “The scientists identified that the metabolite NAD+, which is naturally present in every cell of our body, has a key role as a regulator in protein-to-protein interactions that control DNA repair.” This is a huge breakthrough in anti-aging!

This has all led to a natural form of detox therapy based in the science of Orthomolecular Therapy. The term was coined by professor and psychiatrist Abram Hoffer. In the 1950’s, Hoffer gave high doses of niacin to people with schizophrenic episodes. Bill Wilson, the co-founder of AA, was so thrilled by the effects of niacin, that he dedicated 11 years of his life from 1960-1971 to the study, research and treatment of alcoholic schizophrenics. Wilson organized the very first Schizophrenic’s Anonymous group in Saskatoon, which was very successful. All group members took large dosages of niacin daily. The niacin that can be purchased in a retail store has some helpful effects, but very limited. This is similar to the NAD pills that can be purchased online. They offer some similar effects as NAD+ treatment, but limited.

The United States Patent Office delayed issuing a patent on the Wright brothers’ airplane for five years because it broke accepted scientific principles. This is actually true. And so is this: Vitamin B-3 – niacin – is scientifically proven to be effective against psychosis, yet the medical profession has delayed endorsing it. Not for five years, but for fifty plus years! Abram Hoffer stated, “Vitamin B-3 exists as the amide in nature, in nicotinamide adenine dinucleotide (NAD). Pure nicotinamide and niacin are synthetics. Niacin was known as a chemical for about 100 years before it was recognized to be vitamin B-3. It is made from nicotine, a poison produced in the tobacco plant to protect itself against its predators, but in the wonderful economy of nature which does not waste any structures, the nicotine is simplified by cracking open one of the rings, thus becoming the immensely valuable vitamin B-3.”

Abram Hoffer said, “To my astonishment and delight, there were almost an immediate response and patients who would ordinarily take 3 to 6 months to shows an adequate response to vitamin B3 were responding on NAD in days and weeks”. Abram Hoffer’s central study concluded that illness, including mental illness, is not caused by drug deficiency. But much illness, especially mental illness, may be caused by a vitamin deficiency. This makes sense and has stood up in clinical trials again and again. The benefits include good cholesterol levels, sleep improvement, appetite, glowing skin, reduction or elimination of cravings, revitalization and restoration of brain cells. Overall, the whole body improves. One might think doctors would run to offer magical NAD+ to their patients.

There are a few ways to administer NAD+ to the body. There is the oral component; however, this does not work as well as other applications. There is also the nasal version which is being used during aftercare, and it works well for better clearance. There is also an experimental patch undergoing research as I am writing this. The most revolutionary effect comes from the intravenous protocol. It is a ten day protocol that is being perfected by Dr.Mestayer. Dr.Mestayer comes from the swamps of Louisiana and has been researching and practicing for over 14 years with 1000 patients from all over the world. Those same patients reported very minimal to 0 cravings after the treatment and have been able to come back to their daily functions, which is absolutely astonishing. Dr.Mestayer has been able to help patients with PTSD and neurodegenerative diseases, arthritis and depression. One would ask, “How come there’s no FDA approval and more clinical research for this treatment?” If you can vividly see on the second or third day a person’s skin glowing and cognitive skills returning to crisp functionality, then why won’t the government jump in to help millions of suffering addicts? There are a lot of unanswered questions, but we know one fact- NAD+ is utilizing one’s own body to heal and that is a magnificent fact.

And here is more good news. This therapy is appropriate for anyone with:
● any chronic condition or “auto-immune disease”
● any unknown, strange, undiagnosed illness
● any chronic pain from an injury or illness
● high blood pressure
● high cholesterol
● diabetes
● any addictions
● low energy
Side effects include flushing and some dizziness, which later goes away.

For years, NAD+ was ordered from Africa where it has been available for quite a while, but there are now producers of 100% solution here in the United States. There are NAD centers in Great Britain, Australia, California, Arizona, and we now have access to it here at home in South Florida.